grant

Ancient proteins and disease. [ 2011 - 2013 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1008667]

Researchers: A/Pr Todd Mitchell (Participant) Prof Roger Truscott (Principal investigator)

Brief description Most diseases are much more common in the elderly. The reasons are poorly understood. We have evidence that the most common eye diseases, cataract and presbyopia, are due to the fact that the large molecules that make up the lens do not turnover. In lenses of older people proteins, which make up the bulk of the transparent tissue, become degraded. It turns out that very long lived proteins are quite common in the body. This proposal seeks to determine what role degradation of these ancient proteins has in other diseases of aging.

Funding Amount $AUD 516,207.04

Funding Scheme Project Grants

Notes Standard Project Grant

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