[Cite as http://purl.org/au-research/grants/arc/FL140100027]
Researchers Prof Antoine van Oijen
Brief description Living cells are filled with complex protein machines that are responsible for the molecular processes supporting life. This project is aimed towards the development of physical tools that enable the study of these protein complexes at the level of single molecules. The researchers involved will study the protein machinery responsible for DNA replication, the process of duplicating genomic information before cell division. By making real-time single-molecule movies of the replication process they will unravel the molecular mechanisms of this important process and provide the fundamental knowledge required to understand disease mechanisms and catalyse drug development.
Funding Amount $2,898,150
Funding Scheme Australian Laureate Fellowships