[Cite as http://purl.org/au-research/grants/arc/DP150101674]
Researchers Prof Hans Griesser; Dr Bryan Coad; Prof Harm-Anton Klok; Prof Nick Read
Brief description This project will establish a scientific basis for the design and development of thin coatings, for use on biomedical devices, that can resist the attachment of fungal cells and the ensuing formation of infectious fungal biofilms on their surfaces. Advancing mechanistic understanding of how physico-chemical properties of materials surfaces in?uence fungal attachment will enable rational development and optimisation of coating chemistries and structures. Tethered antifungal compounds will be added to polymer surfaces by controlled polymerisation methods to provide active deterrence; factors such as conformational flexibility will be studied to optimise coatings, which will prevent life-threatening infections and reduce healthcare costs.
Funding Amount $355,500
Funding Scheme Discovery Projects