[Cite as http://purl.org/au-research/grants/arc/DP180102727]
Researchers Prof Abdul Sattar; Prof Shoba Ranganathan; Prof Jayaram Bhyravabhotla
Brief description This project aims to develop novel and efficient heuristic-based algorithms leading to near accurate protein tertiary structure models. Knowledge about protein structures is fundamental to our understanding of living systems. The progress on experimental determination of these structures has been extremely limited and remains an open challenge in molecular biology. Computational prediction of protein structures from sequences is emerging as a promising approach, but its accuracy is far from satisfactory. The software systems developed in this project will be used in structural identification of target proteins in drug design. This will make drug design process more efficient, saving time and cost, potentially saving lives.
Funding Amount $438,211
Funding Scheme Discovery Projects