Dissecting Spatial, Regional and Temporal Aspects of the Cancer Epigenome [ 2014 - 2017 ]

Also known as: Epigenetic Remodelling in Cancer

Research Grant

[Cite as]

Researchers: Dr Clare Stirzaker (Participant) Prof Susan Clark (Principal investigator)

Brief description Epigenetic deregulation occurs commonly in cancer, and can affect not only single genes but can encompass large chromosomal domains, leading to altered expression of oncogenes and tumour suppressor genes, and genomic instability. We will investigate the role of epigenetic remodeling, how spacial reorganisation of the genome, nuclear architecture, chromatin looping and replication timing may affect long range epigenetic deregulation, and ultimately contribute to cancer formation and progression.

Funding Amount $AUD 690,216.18

Funding Scheme Project Grants

Notes Standard Project Grant

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