Functional significance of subcellular localisation of viral 3C protease in rhinovirus pathogenesis [ 2009 - 2013 ]

Also known as: Role of viral 3C protease in rhinovirus pathogenesis

Research Grant

[Cite as]

Researchers: Prof Reena Ghildyal (Principal investigator)

Brief description Rhinovirus (RV) infections are the major cause of virus induced asthma attacks and common colds, causing significant morbidity and mortality. The incidence of asthma is increasing worldwide with new strategies urgently needed to reduce RV-associated disease. We have observed RV 3C protease in the nuclear compartment of infected host cells and propose to determine its significance in RV pathogenesis with relevance to asthma therapies.

Funding Amount $AUD 613,513.79

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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