grant

Identifying the role of airway stem cells in maintaining lentiviral mediated gene expression for cystic fibrosis lung disease [ 2016 - 2018 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1098127]

Researchers: A/Pr David Parsons (Principal investigator) A/Pr Ivan Bertoncello Dr Martin Donnelley Dr Timothy Kuchel (Participant)

Brief description Cystic fibrosis (CF) is a progressive, chronic and debilitating genetic disease that casuses early death from lung disease. Although drug treatments for a few of the ~2000 CF mutations have appeared, only a genetic therapy can treat all CF mutation types. This project will assess whether a novel airway pre-treatment improves the level and duration of lentiviral gene transfer, and whether effective long-term gene expression is the result of transducing resident airway basal stem cells.

Funding Amount $AUD 836,567.28

Funding Scheme Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Identifiers
Viewed: [[ro.stat.viewed]]