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Linkage Infrastructure, Equipment and Facilities - Grant ID: LE150100163 [ 2015 - 2015 ]

Research Grant

[Cite as http://purl.org/au-research/grants/arc/LE150100163]

Researchers Prof Katharina Gaus; Prof John Gooding; Dr Till Boecking; Dr Lawrence Lee; Prof James Whisstock; Prof Jamie Rossjohn; Prof Paul Hertzog; Prof William Heath; Prof Dale Godfrey; Dr Daniel Hatters; A/Prof Harry Quiney; A/Prof Brian Abbey; A/Prof Filip Braet; Prof Nicholas King; Prof Georges Grau; Prof Antoine van Oijen; Prof Ewa Goldys; Prof Johnson Mak; Prof Frederic Meunier; Prof Alpha Yap; Dr Nicholas Eyre; Prof Sarah Russell

Brief description The goal of the proposal is to establish a single molecule imaging laboratory to close the century-old gap between structural imaging and cellular imaging. Utilising the expertise of the ARC Centre of Excellence in Advanced Molecular Imaging, we will design, build and apply three microscopes that go beyond the current commercial solutions for single molecule localisation microscopy (PALM, STORM) and perform single molecule imaging (i) deep inside cells and tissue, (ii) with fast acquisition rate to monitor highly dynamic molecular events, and (iii) improved precision to image molecules and complexes in intact cells with = 1nm resolution. There is no comparable imaging facility in the world.

Funding Amount $560,000

Funding Scheme Linkage Infrastructure, Equipment and Facilities

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