grant

Linkage Infrastructure, Equipment and Facilities - Grant ID: LE160100047 [ 2016 - 2016 ]

Research Grant

[Cite as http://purl.org/au-research/grants/arc/LE160100047]

Researchers A/Prof Martin Scanlon; Prof Joel Mackay; A/Prof Paul Gooley; Prof Raymond Norton; Prof Nicholas Dixon; Prof Peter Lewis; Prof Peter Scammells; Prof Jacqueline Matthews; A/Prof Aaron Oakley; Dr Ann Kwan; A/Prof Richard Hughes

Brief description Distributed facility for fragment based drug discovery: The facility aims to provide researchers with the ability to generate small molecules that modulate therapeutically and biologically important protein targets. Fragment-based drug design (FBDD) provides a rational approach to generate such biologically active compounds. The facility is designed to allow researchers throughout Australia to access the necessary infrastructure to undertake FBDD projects against a range of biologically important targets. The facility aims to enable access to high-throughput nuclear magnetic resonance spectroscopy and surface plasmon resonance, and to generate the capacity for automation in chemical synthesis and sample preparation to expedite the development of novel bioactive molecules. The development of better approaches to hit development may benefit many researchers in Australia employing FBDD.

Funding Amount 380000

Funding Scheme Linkage Infrastructure, Equipment and Facilities

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