[Cite as http://purl.org/au-research/grants/arc/LP140100095]
Researchers Dr Blaine Roberts; Dr Dominic Hare; Dr Gawain McColl; Adj/Prof Rudolf Grimm
Brief description Systems biology uses advanced analytical technology to study the complex chemistry of the living cell. Many cellular functions are the result of chemical reactions involving metalloproteins, which are notoriously difficult to study due to the weak bonds between metal and protein that is not normally amenable to traditional proteomic approaches. In partnership with the leading analytical manufacturer Agilent Technologies, we will adapt and apply advanced mass spectrometry to the study of metalloproteins, developing new methods for studying hundreds of molecules in single experiments. Using the C. elegans model organism, we will showcase the importance of metals in biology and develop new solutions for the $2.9 billion proteomics industry.
Funding Amount 229960
Funding Scheme Linkage Projects