Longitudinal assessment of neuropathy in type 1 diabetes using novel ophthalmic markers (LANDMark)

Research Project

Researchers: Emeritus Professor Nathan Efron (Principal investigator, Associated with) Dr Katie Edwards (Participant)

Full description The LANDMark study is an investigator-masked, prospective, longitudinal, controlled, natural history (observational) study conducted at two sites – Brisbane, Australia and Manchester, UK. The LANDMark study aims to: observe the natural history of diabetic neuropathy using novel non-invasive ophthalmic tests; prospectively characterise changes in corneal and retinal structural and functional (corneal subbasal nerve plexus, corneal sensation threshold, retinal thickness and retinal sensitivity) parameters in individuals with and without diabetic neuropathy; determine the predictive validity of the tests to measure these; and identify demographic and metabolic risk factors associated with these changes over time.

Data time period: 08 2009 to 31 08 2014

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  • Local : 10378.3/8085/1018.15776
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Contact Information

Postal Address:
Dr Nicola Pritchard