grant

Physiological and pathological effects of oxidation on contractile function in skeletal muscle [ 2013 - 2016 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1051460]

Researchers: Prof Graham Lamb (Principal investigator) ,  A/Pr Robyn Murphy Prof Michael Mckenna

Brief description Reactive oxygen molecules generated within muscle fibres in normal exercise and in pathological conditions, greatly affect muscle function by altering the responsiveness of the contractile proteins. This study investigates how various oxidative stresses affect particular reactive sites on key proteins controlling muscle contraction. The findings should identify key molecular changes involved in normal activity and the role oxidation plays in chronic muscle weakness in particular conditions.

Funding Amount $AUD 613,311.63

Funding Scheme Project Grants

Notes Standard Project Grant

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