grant

Protein Disulphide Isomerase and Neurodegeneration in Motor Neuron Disease [ 2011 - 2014 ]

Also known as: Protein Disulphide Isomerase and Motor Neuron Disease

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1006141]

Researchers: A/Pr Julie Atkin (Principal investigator) Prof Malcolm Horne (Participant)

Brief description Motor Neuron Disease (MND) patients currently face a bleak future. In the common global form of disease, the average length of survival after diagnosis is 31 months. Current therapies have at best a modest effect on the course of the disease with little or no benefit in terms of overall patient survival. We have new evidence that a protein called PDI can prevent the motor neuron cells from dying in MND and hence this may be a novel therapeutic target for both sporadic and familial forms of MND.

Funding Amount $AUD 318,517.71

Funding Scheme Project Grants

Notes Standard Project Grant

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