Role of the host fibrinolytic system in invasive group A streptococcal disease [ 2010 - 2014 ]

Also known as: Group A streptococcus and the fibrinolytic system

Research Grant

[Cite as]

Researchers: Dr Martina Sanderson-Smith (Principal investigator)

Brief description The flesh-eating bacterium group A streptococcus (GAS) is estimated to cause 700 million cases of self-limiting disease, and 600,000 cases of serious invasive disease each year. Approximately 25% of invasive infections are fatal. We have shown that GAS are able to hijack the host fibrinolytoc system to cause severe invasive infections. We plan to further examine the details of how this contributes to GAS disease. This research may contribute to the future devlopment of new therapeutics.

Funding Amount $AUD 531,444.73

Funding Scheme Project Grants

Notes New Investigator Grant

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