grant

The role of mutant cyclin F in amyotrophic lateral sclerosis [ 2016 - 2018 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1107644]

Researchers: A/Pr Ian Blair (Principal investigator) A/Pr Julie Atkin A/Pr Justin Yerbury Dr Lezanne Ooi Prof Roger Chung (Participant)

Brief description Amyotrophic lateral sclerosis (ALS, also known as motor neuron disease, MND) is characterised by rapid paralysis leading to death within 2 to 5 years of onset. There are no effective diagnostic tests or treatments. Confusion remains around the primary cause of paralysis. We recently discovered ALS gene mutations that disrupt normal nerve function, a process known as abnormal protostasis. This gives us a unique opportunity to unlock the primary cause of paralysis and develop animal models of ALS

Funding Amount $AUD 1,041,704.04

Funding Scheme Project Grants

Notes Standard Project Grant

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