Roles of muscarinic M3 receptors in antipsychotic-induced metabolic side-effects: prevention and treatment of antipsychotic-induced insulin dysregulation [ 2013 - 2016 ]

Also known as: Muscarinic M3 receptors and antipsychotic-induced metabolic side-effects

Research Grant

[Cite as]

Researchers: Prof Chao Deng (Principal investigator) Prof Xu-Feng Huang (Participant)

Brief description Antipsychotic drugs are used to treat various mental disorders, such as schizophrenia, bipolar disorder, dementia and major depression. However, these drugs cause serious metabolic side-effects leading to premature death and huge costs to the Australian health care system. This project aims to reveal the role of muscarinic M3 receptors in antipsychotic-induced insulin dysregulation that precedes diabetes. Understanding these mechanisms will provide new strategies for the prevention and treatment of these critical adverse effects.

Funding Amount $AUD 603,825.41

Funding Scheme Project Grants

Notes Standard Project Grant

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