grant

Roles and regulation of sphingosine kinase 1 during dengue virus infection [ 2013 - 2015 ]

Also known as: Dengue virus and sphingosine kinase

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1044212]

Researchers: Dr Jillian Carr (Principal investigator) Prof Stuart Pitson (Participant)

Brief description Dengue virus (DENV) infection is a global human disease with an estimated 50 million infections annually and there is no vaccine or therapy. DENV disease is worsended by the way the body responds to infection and we have investigated these responses. We know the virus changes a molecule in the body called sphingosine-kinase 1 (SK1), which normally controls if cell live or die and how they function. This study will characterise how DENV influences SK1 and if we can target this interaction to develop new drugs against DENV infection.

Funding Amount $AUD 482,795.52

Funding Scheme Project Grants

Notes Standard Project Grant

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