Dataset

Tag single nucleotide polymorphisms (SNPs) in CYP1B1 - investigation of effect on Primary Open Angle Glaucoma (POAG) dataset

Flinders University
Dr Kathryn Penelope Burdon (Associated with, Aggregated by) Jamie Craig (Aggregated by) Kathryn Penelope Burdon (Associated with, Aggregated by) Prof Jamie Craig (Aggregated by)
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=http://hdl.handle.net/2328.1/1096&rft.title=Tag single nucleotide polymorphisms (SNPs) in CYP1B1 - investigation of effect on Primary Open Angle Glaucoma (POAG) dataset&rft.identifier=http://hdl.handle.net/2328.1/1096&rft.publisher=Flinders University&rft.description=This dataset comprises cleaned, standard genetics data of the CYP1B1 gene from 1810 samples. Seven tag single nucleotide polymorphisms (SNPs), including two coding variants (L432V and N543S), were genotyped in 860 primary open angle glaucoma (POAG) cases and 898 examined normal controls. Each SNP and haplotype was assessed for association with disease. Relevant column headings for the *.ped file are: Family ID Individual ID Father ID Mother ID Sex Affection status Then the remainder describe genotypes at single nucleotide polymorphisms, as described in the *.map file, 2 columns per SNP In the *.map file: Chromosome SNP name Position in centiMorgans Position in basepairs&rft.creator=Dr Kathryn Penelope Burdon&rft.creator=Prof Jamie Craig&rft.creator=Jamie Craig&rft.creator=Kathryn Penelope Burdon&rft.date=2013&rft.relation=http://www.molvis.org/molvis/v16/a245/&rft.coverage=AU&rft_rights=Copyright (c) 2010 Flinders University, South Australia&rft_rights=CC BY: Attribution 3.0 AU http://creativecommons.org/licenses/by/3.0/au&rft_subject=Gene Frequency&rft_subject=Linkage Disequilibrium&rft_subject=Cytochrome P-450 Enzyme System&rft_subject=Aryl Hydrocarbon Hydroxylases&rft_subject=Ophthalmology&rft_subject=Medical and Health Sciences&rft_subject=Optometry and Ophthalmology&rft_subject=Quantitative Genetics (Incl. Disease and Trait Mapping Genetics)&rft_subject=Biological Sciences&rft_subject=Genetics&rft_subject=Hearing, Vision, Speech and Their Disorders&rft_subject=Health&rft_subject=Clinical Health (Organs, Diseases and Abnormal Conditions)&rft_subject=Strategic Basic Research&rft.type=dataset&rft.language=English Go to Data Provider

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CC-BY

CC BY: Attribution 3.0 AU
http://creativecommons.org/licenses/by/3.0/au

Copyright (c) 2010 Flinders University, South Australia

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This dataset is available for reuse under license.

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Full description

This dataset comprises cleaned, standard genetics data of the CYP1B1 gene from 1810 samples. Seven tag single nucleotide polymorphisms (SNPs), including two coding variants (L432V and N543S), were genotyped in 860 primary open angle glaucoma (POAG) cases and 898 examined normal controls. Each SNP and haplotype was assessed for association with disease.

Relevant column headings for the *.ped file are:
Family ID
Individual ID
Father ID
Mother ID
Sex
Affection status

Then the remainder describe genotypes at single nucleotide polymorphisms, as described in the *.map file, 2 columns per SNP

In the *.map file:
Chromosome
SNP name
Position in centiMorgans
Position in basepairs

Data time period: 2010 to 06 2010

166.7429167,-0.6911344 166.7429167,-51.6633232 100.0911072,-51.6633232 100.0911072,-0.6911344 166.7429167,-0.6911344

133.41701195,-26.1772288

iso31662: AU

Identifiers