grant

Understanding age-related protein aggregation. The mechanism of cataract and its prevention [ 2014 - 2017 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1068087]

Researchers: Prof Andrew Abell Prof Roger Truscott (Participant) Prof John Carver (Principal investigator)

Brief description Cataract arises from clouding of the eye lens due to the aggregation of crystallin proteins whose high concentration and close packing facilitate lens transparency. This proposal will investigate crystallin structure and interactions to understand the reasons for cataract formation and its prevention via the design of aggregation inhibitors. The results will facilitate the development of drugs to prevent cataract and other related protein aggregation diseases, e.g. Alzheimer’s and Parkinson’s.

Funding Amount $AUD 709,333.31

Funding Scheme Project Grants

Notes Standard Project Grant

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