grant

Understanding the role of caspase-2 in cellular stress response and ageing [ 2012 - 2016 ]

Also known as: A novel determinant of stress response and ageing

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1021456]

Researchers: Prof Sharad Kumar (Principal investigator)

Brief description This project builds upon our recent findings showing that a protein, called caspase-2, is involved in protecting against oxidative damage and ageing in a mouse model. We propose to carry out further studies to fully understand how caspase-2 regulates cell’s response to oxidative stress. Such studies will be critical in assessing if caspase-2 or its substrates are useful targets for drugs to treat diseases that may arise due to cell’s inability to properly respond to oxidative damage.

Funding Amount $AUD 918,516.98

Funding Scheme Project Grants

Notes Standard Project Grant

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